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pentobarbital will minimize the level or impact of elbasvir/grazoprevir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic result of elbasvir/grazoprevir could be lessened if coadministered with sturdy CYP3A inducers and is for that reason contraindicated.C: Use with caution if Positive aspects outweigh chall